2013년 10월 22일, 바로셀로나 ICOMS에서
아주대학교병원 이정근 교수, 자가치아뼈이식 강연
2013년 10월 22일, 아주대학교병원 이정근 교수의 “Autogenous tooth bone, its theoretical background and practice in clinical dentistry” 강연이 바로셀로나에서 진행되는 21st International Conference on Oral and Maxillofacial Surgery에서 란 주제의 특별포럼으로 진행됩니다.
이정근 교수는 한국자가치아뼈은행 운영위원이자 한국치아은행의 연구위원으로 본사의 자가치아뼈이재를 이용하여 수많은 임상 및 논문을 발표 하여 왔습니다.
ICOMS의 초청으로 이루어지는 본 강연에 많은 관심 부탁드립니다.
Abstract :
Title: Autogenous tooth bone, its theoretical background and practice in clinical dentistry
Lecturer : Jeong Keun Lee
Division of Oral and Maxillofacial Surgery
Department of Dentistry, Ajou University School of Medicine
It’s been almost 50 years since 1967 when Urist group first reported bone induction by decalcified dentin right after the report of autoinduction of the decalcified bone by Urist in 1965. The biochemistry textbook has already stated that the basic component of the bone and dentin is almost the same.
AutoBT is developed upon this idea applying the idea of recycling the extracted teeth. Unlike bovine bone or allogenic bone which must be heat treated, AutoBT contains the organic component because it is of self origin. The same principle of osteoinduction by autogenous bone applies to the AutoBT because of the BMPs remained in the organic component. Many techniques including SEM, EDS, and XRD detailed the inorganic component of the AutoBT, which is the normal component of the viable bone. It contains HAP, ¥â-TCP, OCP and ACP, all components excluding brushite which is the main component of the pathologic tissue such as gall stone or salivary stone. Moreover, low crystalline structure of the viable tissue is retained in the AutoBT because of the processing technology excluding heat treatment, which is adequate for biological process such as bone remodelling.
Evaluation of bone graft is based on the histological evidence of a microscopic activity conducted by vital bone tissue in vivo. It can be evidenced by bone remodelling, which means the viable osteoclast and osteoblast is available by the bone grafting procedures. It is therefore one of the criteria for bone graft materials to be incorporated in the bone remodelling procedures. We evaluated the bone remodelling capacity of the AutoBT in vivo using the miniature pig system with a good result. New bone was growing at the periphery of the existing bone showing the evidence of bone remodelling.
AutoBT has the advantage, but without the disadvantage of autogenous bone. It is immunologically completely a self, equivalent to autogenous bone, and no other donor site morbidity except the effort of extraction. AutoBT not only can be used as a filling material but also can bear the occlusal stress of the dental implants. Auto BT graft can be done in the dental office under the local anesthesia as an additional procedure of extraction and the recycling of the extracted teeth can be another advantage of this technique. Considering of all these, AutoBT grafting is expected to extend the realm of the dentistry encompassing a wide range of bone graft and regeneration.
